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5 Best Sinus Medicines of 2025

Last Updated - 2025/09/16

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Buckley's

Buckley's Cough Syrup, Complete Extra Strength Mucus Relief, Cough & Cold & Flu Medicine, Headache and Sinus Relief, 250 mL (Packaging May Vary)

Buckley's

CA$18.47

More Details
Main highlights
- This package includes one 250 mL bottle of Buckley's Complete Plus Extra Strength Mucus Relief Syrup
- Manage your cold symptoms with Buckley's Complete Plus Extra Strength Mucus Relief Syrup, providing fast-acting relief of minor aches and pains, fever and chills, sore throat pain, wet cough, nasal and sinus congestion, and chest congestion
- Formulated for adults and children 12 years and older, take 2 teaspoons (10 mL) every 4-6 hours (do not take more than 40 mL in 24 hours). Do not take more than directed. If preferred, mix with equal parts honey
- For medicinal ingredients, each teaspoon (5 mL) of Buckley's Complete contains 325 mg acetaminophen for reducing fever and relieving aches and pain, 200 mg of the guaifenesin expectorant to loosen mucus and phlegm buildup, and 20 mg of menthol to suppress your cough and relieve nasal congestion
CA$18.47
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

MOXE

MOXĒ Eucalyptus Essential Oil Nasal Inhaler, Sinus & Congestion Relief, Daily Relaxation, Therapeutic No-Mess Aromatherapy, Pure and Natural, Made in USA (3 Pack)

MOXE

CA$14.99

More Details
Main highlights
- Relief right in your hand - With their compact form, our inhalers are easy & safe to use multiple times per day. Place near one nostril, inhale and exhale. Then switch sides. It’s that easy!
- Pure eucalyptus essential oil - Made with only one ingredient, 100% pure eucalyptus oil, and with no additives, no fillers, and alcohol-free.
- No-mess aromatherapy - MOXĒ Inhalers are a liberating way to practice aromatherapy. Unlike oil diffusers, it’s a hassle-free & mess-free way to relieve sinuses and congestion anywhere and everywhere.
- No-mess aromatherapy - MOXĒ Inhalers are a liberating way to practice aromatherapy. Unlike oil diffusers, it’s a hassle-free & mess-free way to relieve sinuses and congestion anywhere and everywhere.
- Made in America - These are made with 100% pure essential oils. They're naturally very strong and can cause discomfort if inhaled aggressively.
- Authentic fragrance - Pure form eucalyptus oil gives off a woodsy, yet sweet, aroma. Alcohol-free and no additives means a clean scent with no chemical notes.
CA$14.99
3
Best Value
11% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol
11% Off

TYLENOL Sinus Extra Strength eZ Tabs, Relieves Sinus congestion and other Sinus symptoms, Daytime and Nighttime, Convenience Pack, 40ct

Tylenol

CA$11.27

CA$12.77
(11% Off)

More Details
Main highlights
- Tylenol Sinus Extra Strength Daytime/Nighttime Combo, 24+16 pack, helps relieves your day and night sinus symptoms
- Night tablets also contain 2 mg of Chlorpheniramine Maleate as an antihistamine for runny nose and sneezing
- Get fast, effective relief of symptoms including sinus-related pain and pressure, sinus headache, sinus congestion, aches and pains and runny nose and sneezing (nighttime only) due to the common cold or flu
- For adult uses only (12 years and older). Take 1-2 caplet tablets every 4 hours as needed; Do not exceed a combined total of any 8 caplets in 24 hours
- Each day and night tablet contains 500 mg of Acetaminophen to help relieve pain and reduce fever, 5 mg of Phenylephrine Hydrochloride for nasal decongestion
CA$11.27
CA$12.77 (11% Off)
4

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol

TYLENOL Extra Strength Sinus eZ Tabs, Relieves Sinus congestion and other sinus Symptoms, Daytime, 40ct

Tylenol

CA$11.27

CA$12.47
(9% Off)

More Details
Main highlights
- To use, Adults and children 12 years and older, take 1-2 daytime tablets every 4 hours as needed
- Made with 500 mg of Acetaminophen for help relieve pain and reduce fever and 5 mg of Phenylephrine Hydrochloride for nasal decongestion
- Made in an easy-to-swallow tablet form
- Get effective relief of symptoms including nasal congestion, sinus pain and pressure, fever, sore throat, and headache due to the common cold or flu
- 40-count package of Tylenol Sinus Extra Strength Day Time Tablets help relieve your morning sinus symptoms
CA$11.27
CA$12.47 (9% Off)
5

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

BENYLIN

BENYLIN Extra Strength Cold and Sinus Caplets, Relieves Cold and Sinus symptoms, Daytime and Nighttime, Convenience Pack, 20ct

BENYLIN

CA$9.64

More Details
Main highlights
- Night tablets also contain 2 mg of antihistamine Chlorpheniramine Maleate to relieve runny nose and sneezing
- Get fast, effective relief of sinus pain, nasal congestion, headache and fever
- Each package contains 20 tablets with 10 Day tablets and 10 Night tablets
- Both Day and Night tablets contain 5 mg of decongestant Phenylephrine Hydrochloride to relieve nasal congestion and 500 mg of analgesic Acetaminophen to relieve sinus pain, headache and fever
- Benylin Extra Strength Cold and Sinus Day/Night Tablets, 20 Count, are a portable and convenient solution to relief your cold and sinus symptoms during the day and night
CA$9.64

5 Best Sinus Medicines of 2025

Buckley's Cough Syrup, Complete Extra Strength Mucus Relief, Cough & Cold & Flu Medicine, Headache and Sinus Relief, 250 mL (Packaging May Vary)

MOXĒ Eucalyptus Essential Oil Nasal Inhaler, Sinus & Congestion Relief, Daily Relaxation, Therapeutic No-Mess Aromatherapy, Pure and Natural, Made in USA (3 Pack)

TYLENOL Sinus Extra Strength eZ Tabs, Relieves Sinus congestion and other Sinus symptoms, Daytime and Nighttime, Convenience Pack, 40ct

TYLENOL Extra Strength Sinus eZ Tabs, Relieves Sinus congestion and other sinus Symptoms, Daytime, 40ct

BENYLIN Extra Strength Cold and Sinus Caplets, Relieves Cold and Sinus symptoms, Daytime and Nighttime, Convenience Pack, 20ct

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