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5 Best Enzyme Cleaners of 2025

Last Updated - 2025/09/17

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

ANGRY ORANGE

Odor Eliminator - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies

ANGRY ORANGE

CA$54.26

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Main highlights
- Whatever the smell, we'll send it to hell! Our fragrant enzyme cleaner is a ruthless pet muck eliminator - it doesn't mask unpleasant odors and stubborn stains, it eradicates them! Fighting fresh!
- Pets do what they want, where they want - but with our enzymatic cleaner they've met their match! Suitable for carpets, hardwood floors, furniture, or even the yard, this carpet cleaner spray will prevail!
- Our carpet cleaner solution uses natural enzymes to destroy marks and smells. The pet stain remover activates upon contact, breaking down the stain, and dissipating the odor for up to 80 hours!
- If you're struggling to think of gifts for Fido - this upholstery cleaner is a gentle reminder he needs to do his business at walkies time, and not at half time! A carpet deodorizer to keep everyone happy.
- At Angry Orange our fragrant carpet stain remover has been formulated with naturally fresh citrus scents, which are safe to use around both pets and children.
CA$54.26
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Eco Strong

Cat Stain And Odor Remover | Enzyme Urine Odor Neutralizer - Stain Remover for Carpet, Litter Boxes, Bedding, and Laundry [Citrus Scent, 128 Oz]

Eco Strong

CA$49.97

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Main highlights
- Use On Laundry: Use in the wash on soiled pet beds, reusable piddle pads and laundry. If your cat likes to pee on your bedding, wash with Eco Strong, and the odor will disappear.
- Professional Strength & Non Toxic: EcoStrong is made without any toxic chemicals. The powerful formula is tough on stains but gentle on surfaces!
- Erase Pet Stain and Odors: Eco Strong is a bio-enzymatic odor remover and highly effective multipurpose cleaner for pet accidents. It doesn't mask urine odors - it eliminates them at the source.
- Easy To Use: Just spray, saturate, and gently blot/wipe and watch the pet damaged spots disappear. The only thing left behind is a gentle citrus scent.
- All-purpose & Multi-surface: Effective on any organic mess in all areas of your home from carpets, furniture, car upholstery, crates, litter boxes, & more.
CA$49.97
3

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

ez-clean

ez-clean Advanced Odor Remover- Highly Concentrated Bio Enzyme - Pet Odor Eliminator for Dog, Cat, and Small Animal Urine - Indoor & Outdoor Use for Any Organic Spills (4L jug)

ez-clean

CA$49.95

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Main highlights
- Provides excellent breakdown of organic substances such as urine, blood, vomit, feces and sweat
- Professional, highly concentrated bioenzyme cleaner containing 12 billion bioenzymes per 32oz
- Liquid blend of safe, naturally occurring bacteria that eliminates odors and degrades organic waste
- Eliminates odors instead of masking them
- Can be used full strength or diluted to 1:64 and still be highly effective
CA$49.95
4
Best Value

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

ez-clean

ez-clean Advanced Odor Remover- Highly Concentrated Bio Enzyme Pet Odor Eliminator for Dog, Cat, and Small Animal Urine Indoor & Outdoor Use for Any Organic Spills(1 L (Pack of 1))

ez-clean

CA$19.95

CA$21.45
(6% Off)

More Details
Main highlights
- SAFE ON EVERY SURFACE – safe on all indoor and outdoor surfaces.
- INDOOR AND OUTDOOR - Can be used full strength indoors or directly on your dog for skunk smell or diluted to 1:64 and sprayed outdoors. It will even eat the urine creating the brown spot and allow the grass to grow back.
- EXCELLENT BREAKDOWN of organic substances such as urine, blood, vomit, feces and sweat
- ADVANCED ODOUR REMOVER – Professional grade and highly concentrated naturally occurring enzymatic bacteria that gets rid of odours, degrades organic waste and removed smells.
CA$19.95
CA$21.45 (6% Off)
5

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

ACTIVE

Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

ACTIVE

CA$29.95

More Details
Main highlights
- Value 64 Load Package: ACTIVE Enzyme Cleaner Concentrated 32-oz size is good for 64 Loads compared to other products with 1 lb or less
- Powerful Bio Enzymatic Cleaner: ACTIVE Laundry Odor Removers Boost your normal laundry detergent to effectively target Stains & Odors, not mask them like washing soda or in-wash scent boosters. It uses Lab-proven Biological Cleaning to remove laundry odor & strong smell
- Heavy Duty Stain Remover for clothes: Our Enzyme Laundry Additive Powder is formulated for Stain Removal of dirty clothes, perfect for Funk, Grease, Armpit Sweat stain, Blood stain, Oil and more!
- Gentle on All Fabrics: Our Fragrance Free Laundry Boost Plant-based Formula uses zero harsh chemicals. Natural enhancer for whites & colors. Even safe for pesky activewear fabrics
- Compatible with all Washers & Detergents: Add Laundry Booster Powder to your usual detergent & cleaners! HE, Front & Top load Washer Approved. Also use as laundry soak pretreat powder in order to treat set-in stain
CA$29.95

5 Best Enzyme Cleaners of 2025

Odor Eliminator - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies

Cat Stain And Odor Remover | Enzyme Urine Odor Neutralizer - Stain Remover for Carpet, Litter Boxes, Bedding, and Laundry [Citrus Scent, 128 Oz]

ez-clean Advanced Odor Remover- Highly Concentrated Bio Enzyme - Pet Odor Eliminator for Dog, Cat, and Small Animal Urine - Indoor & Outdoor Use for Any Organic Spills (4L jug)

ez-clean Advanced Odor Remover- Highly Concentrated Bio Enzyme Pet Odor Eliminator for Dog, Cat, and Small Animal Urine Indoor & Outdoor Use for Any Organic Spills(1 L (Pack of 1))

Enzyme Laundry Booster Odor Remover - 2 lbs Unscented Enzymatic Clothes Stain Cleaner Powder, Natural Deodorizer with Bio Active Enzymes, Detergent Additive Eliminator for Sweat, Oil, Blood - 64 Loads

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ez-clean Advanced Odor Remover- Highly Concentrated Bio Enzyme - Pet Odor Eliminator for Dog, Cat, and Small Animal Urine - Indoor & Outdoor Use for Any Organic Spills(1 L Fragrance Free)

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