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5 Best Cold Medicines of 2026

Last Updated - 2026/05/09

1
Best Choice

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

NEOCITRAN

NEOCITRAN® ES Cold & Sinus Night Lemon

NEOCITRAN

CA$15.49

More Details
Main highlights
- Try the daytime formula from NeoCitran for non-drowsy relief during the day
- Suitable for adults and children ages 12 and older
- NeoCitran's most popular formula provides effective relief from sore throat pain, headache, sinus and nasal congestion, runny nose, and sneezing so you can rest
- Extra-strength nighttime cold and sinus medicine
- Dissolve the contents of a single-dose pouch in boiling water to create a soothing, lemon-flavored bedtime beverage
CA$15.49
2

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

NEOCITRAN

NEOCITRAN® ES Cold & Sinus Night Lemon

NEOCITRAN

CA$14.72

CA$15.49
(5% Off)

More Details
Main highlights
- Try the daytime formula from NeoCitran for non-drowsy relief during the day
- Suitable for adults and children ages 12 and older
- NeoCitran's most popular formula provides effective relief from sore throat pain, headache, sinus and nasal congestion, runny nose, and sneezing so you can rest
- Extra-strength nighttime cold and sinus medicine
- Dissolve the contents of a single-dose pouch in boiling water to create a soothing, lemon-flavored bedtime beverage
CA$14.72
CA$15.49 (5% Off)
3
12% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol
12% Off

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct

Tylenol

CA$11.27

CA$12.77
(12% Off)

More Details
Main highlights
- Tylenol Extra Strength Cold Daytime + Nightime Cool Burst eZ Tabs, 24 + 16 pack, relieves symptoms when colds strike so you can get back to your normal, whatever that is
- Get effective relief of nasal congestion, dry cough, fever, aches and pain, runny nose and sneezing
- Each package contains 40 tablets: 24 Daytime and 16 Nighttime tablets; eZ Tabs format is easy to swallow and provides fast and effective relief
- Each Nighttime tablet also contains 2 mg of Chlorpheniramine Maleate as an antihistamine for runny nose and sneezing. Nighttime relief so you can rest.
- Each Daytime and Nighttime tablet contains 500 mg of Acetaminophen to help relieve pain and reduce fever, 10 mg of Dextromethorphan Hydrobromide for cough suppression, and 5 mg of Phenylephrine Hydrochloride for nasal decongestion
CA$11.27
CA$12.77 (12% Off)
4
Best Value
16% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol
16% Off

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct

Tylenol

CA$10.71

CA$12.77
(16% Off)

More Details
Main highlights
- Tylenol Extra Strength Cold Daytime + Nightime Cool Burst eZ Tabs, 24 + 16 pack, relieves symptoms when colds strike so you can get back to your normal, whatever that is
- Get effective relief of nasal congestion, dry cough, fever, aches and pain, runny nose and sneezing
- Each package contains 40 tablets: 24 Daytime and 16 Nighttime tablets; eZ Tabs format is easy to swallow and provides fast and effective relief
- Each Nighttime tablet also contains 2 mg of Chlorpheniramine Maleate as an antihistamine for runny nose and sneezing. Nighttime relief so you can rest.
- Each Daytime and Nighttime tablet contains 500 mg of Acetaminophen to help relieve pain and reduce fever, 10 mg of Dextromethorphan Hydrobromide for cough suppression, and 5 mg of Phenylephrine Hydrochloride for nasal decongestion
CA$10.71
CA$12.77 (16% Off)
5
12% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Tylenol
12% Off

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Nighttime, 40ct

Tylenol

CA$11.27

CA$12.77
(12% Off)

More Details
Main highlights
- To use, Adults and children 12 years and older, take 1-2 nighttime tablets every 4 hours as needed
- Made with 500 mg of Acetaminophen to help relieve pain and reduce fever and 10 mg of Dextromethorphan Hydrobromide to help suppress coughs
- Made with 5 mg of Phenylephrine Hydrochloride to for nasal decongestion, and 2 mg of Chlorpheniramine Maleate antihistamine to help runny noses and sneezing
- Get effective relief of symptoms including: nasal congestion, dry cough, fever, aches and pains, and runny nose and sneezing due to the common cold or flu
- 40-count package of Tylenol Cold Extra Strength Night Time Tablets help relieve your cold symptoms
CA$11.27
CA$12.77 (12% Off)

5 Best Cold Medicines of 2026

NEOCITRAN® ES Cold & Sinus Night Lemon

NEOCITRAN® ES Cold & Sinus Night Lemon

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Daytime and Nighttime, Convenience Pack, 40ct

TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Nighttime, 40ct

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TYLENOL Extra Strength Cold eZ Tabs, Relieves Cold symptoms, Nighttime, 40ct

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