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5 Best Alternative Pain Reliefs of 2025

Last Updated - 2025/09/17

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

ORVANCE

ORVANCE Orthodontic Wax, Clear Moisture Activated Braces Wax Alternative for Pain Relief, 72 Count

ORVANCE

CA$72.19

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Main highlights
- SIMPLE YET VERSATILE: Easy to apply on braces, clear aligners, or retainers, OrthoDots provide hours of relief. Unlike brace wax or teeth wax, OrthoDots mold around areas, staying in place even with food or drink.
- SAFE, CONVENIENT PACKAGING: Ditch the rows of cera para brackets or orthodontic wax. OrthoDots are sealed individually, making them perfect personal orthodontic supplies. Toss them in bags or pockets, ensuring protection against braces irritation anywhere.
- MOISTURE-ACTIVATED: Unlike traditional wax for braces gum, OrthoDots use moisture-activated technology. They adhere to braces and clear aligner edges, offering a comfortable fit, more pliable than dentalwax or wax for dental use.
- GOES ON CLEAR & LASTS UP TO 24 HOURS: Made of clear medical-grade silicone, OrthoDots are 17 times clearer than regular braces wax. They stay put even while eating or drinking for up to 24 hours. Non-toxic and latex free, they’re a safer and more reliable choice than tooth wax.
- AX THE WAX: OrthoDots are the top choice over traditional dental wax for braces. They're perfect for irritation caused by braces brackets or dental wax for invisalign trays. Moisture-activated, they stick better than orthodontic wax.
CA$72.19
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Medistik

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis Muscle & Joint Pain, 58g, Pack of 2

Medistik

CA$43.99

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Main highlights
- THE STRONGEST: MEDISTIK is by far, the strongest non-prescription topical pain reliever available, best alternative to Pain Relief Cream. Our long-lasting extra strength formula is ideal for serious pain management.
- RESTORE: Once applied, MEDISTIK promotes long-term healing by attacking inflammation in your body and providing lasting recovery and deep pain relief you can rely on.
- PRIME: Use MEDISTIK to prime and relax tight muscles for athletic training, peak performances, and day-to-day activities.
- PERFORM: When you’re in pain, use MEDISTIK to attack it directly. A powerful integrated system fights pain and inflammation at the source instead of masking it.
- ALL IN ONE SOLUTION: MEDISTIK works for tight muscles, chronic pain, pulled muscles, arthritis, joint pain, cramps and more. It also works for day-to-day irritations like sore feet, neck pain and headaches!
CA$43.99
3

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Medistik

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis, Knee, Muscle & Joint Pain (1)

Medistik

CA$24.95

More Details
Main highlights
- THE STRONGEST: MEDISTIK is by far, the strongest non-prescription topical pain reliever available, best alternative to Pain Relief Cream. Our long-lasting extra strength formula is ideal for serious pain management.
- RESTORE: Once applied, MEDISTIK promotes long-term healing by attacking inflammation in your body and providing lasting recovery and deep pain relief you can rely on.
- PRIME: Use MEDISTIK to prime and relax tight muscles for athletic training, peak performances, and day-to-day activities.
- PERFORM: When you’re in pain, use MEDISTIK to attack it directly. A powerful integrated system fights pain and inflammation at the source instead of masking it.
- ALL IN ONE SOLUTION: MEDISTIK works for tight muscles, chronic pain, back pain relief, arthritis pain relief, joint pain, cramps and more. It also works for day-to-day irritations like sore feet, neck pain relief and headache relief.
CA$24.95
4
Best Value

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Ulysses Press

Maximum Pain Relief with Your TENS Unit: Easy, Drug-Free Techniques for Treating Chronic Pain, Muscle Injuries and Common Ailments at Home

Ulysses Press

CA$19.50

CA$21.52
(9% Off)

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Main highlights
CA$19.50
CA$21.52 (9% Off)
5

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

LivRelief

Livrelief Pain Relief Cream for Nerve Pain – Fast-Acting, Long-Lasting Relief with Natural Ingredients – Capsaicin Cream for Shingles, Sciatica Pain Relief & More – No Menthol, Paraben-Free, 50g (Pack of 2)

LivRelief

CA$36.64

CA$38.49
(4% Off)

More Details
Main highlights
- Pack of 2
- LivRelief Nerve Pain Relief Cream provides fast and consistent relief from the agony of nerve pain and allows you to regain control over the life you wish to live.
- LivRelief Nerve Pain Relief Cream delivers the active ingredients quickly and consistently right where you need it.
CA$36.64
CA$38.49 (4% Off)

5 Best Alternative Pain Reliefs of 2025

ORVANCE Orthodontic Wax, Clear Moisture Activated Braces Wax Alternative for Pain Relief, 72 Count

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis Muscle & Joint Pain, 58g, Pack of 2

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis, Knee, Muscle & Joint Pain (1)

Maximum Pain Relief with Your TENS Unit: Easy, Drug-Free Techniques for Treating Chronic Pain, Muscle Injuries and Common Ailments at Home

Livrelief Pain Relief Cream for Nerve Pain – Fast-Acting, Long-Lasting Relief with Natural Ingredients – Capsaicin Cream for Shingles, Sciatica Pain Relief & More – No Menthol, Paraben-Free, 50g (Pack of 2)

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